When the ambassadors declared to him the terms of the treaty he was thrown into a violent rage, and declared the peace to be at once shameful and humiliating.

The gout from which he suffered flew to his heart, and on the following day--August 12, 1484--he died.
Two things he did during his reign to the material advantage of the Church, however much he may have neglected the spiritual.

He strengthened her hold upon her temporal possessions and he enriched the Vatican by the addition of the Sistine Chapel.

For the decoration of this he procured the best Tuscan talent of his day--and of many days--and brought Alessandro Filipeppi (Botticelli), Pietro Vannuccio (Il Perugino), and Domenico Bigordi (IL Ghirlandajo) from Florence to adorn its walls with their frescoes.( 1) 1 The glory of the Sistine Chapel, however, is Michelangelo's "Last Judgement," which was added later, in the reign of Pope Julius II (Giuliano della Rovere).
In the last years of the reign of Pope Sixtus, Cardinal Roderigo's family had suffered a loss and undergone an increase.
In 1481 Vannozza bore him another son--Giuffredo Borgia, and in the following year died his eldest son (by an unknown mother) Pedro Luis de Borgia, who had reached the age of twenty-two and was betrothed at the time of his decease to the Princess Maria d'Aragona.
In January of that same year, 1482, Cardinal Roderigo had married his daughter Girolama--now aged fifteen--to Giovanni Andrea Cesarini, the scion of a patrician Roman house.

The alliance strengthened the bonds of good feeling which for some considerable time had prevailed between the two families.