Indeed, I am sure she has.

For many weeks back, I have noticed her altered appearance and loss of appetite.

It was in vain that I urged her to spare herself for a few weeks and make up the time afterwards.

She steadily urged the necessity of getting into business as soon as possible, and would not give up.

She has sacrificed herself, Mr.Martin, I very much fear, to her devotion to the family." And Mrs.Turner burst into tears.
We need not say how sad and depressed Martin was, on turning away from the house, without the chance of seeing Mary, under the idea, too, of her dangerous illness.