Years later, he reappears--here at Wrychester, where he's bought a practice.

Eventually he has two young people, who are represented as his wards, come to live with him.

Their name is Bewery.

The name of the young woman whom John Brake married was Bewery.

What's the inference?
That their mother's dead--that they're known under her maiden name: that they, without a shadow of doubt, are John Brake's children.