The date is March, 1749.
"M.

is but porely.

Sumtimes I am pain'd to believe this quiett life is not well suted to herr disposishun, having bin acustumed to so much livlinesse and nois.

I hav reproched her with this, but she tolde me, with teres in her eys, to be neare mee and M.and C.was to be happie, and ye it is il helth onlie wich is ye cawse of ye sadnesse.

I pray heaven M.'s helth may be on ye mending hand soone.