In the Aegean Sea the Romano-Rhodian fleet at Samos, after being weakened by detaching the Pergamene ships to the Hellespont to support the land army which had arrived there, was in its turn attacked by that of Polyxenidas, who now numbered nine sail more than his opponents.

On December 23 of the uncorrected calendar, according to the corrected calendar about the end of August, in 564, a battle took place at the promontory of Myonnesus between Teos and Colophon; the Romans broke through the line of the enemy, and totally surrounded the left wing, so that they took or sank 42 ships.

An inscription in Saturnian verse over the temple of the Lares Permarini, which was built in the Campus Martius in memory of this victory, for many centuries thereafter proclaimed to the Romans how the fleet of the Asiatics had been defeated before the eyes of king Antiochus and of all his land army, and how the Romans thus "settled the mighty strife and subdued the kings." Thenceforth the enemy's ships no longer ventured to show themselves on the open sea, and made no further attempt to obstruct the crossing of the Roman land army.
Expedition to Asia The conqueror of Zama had been selected at Rome to conduct the war on the Asiatic continent; he practically exercised the supreme command for the nominal commander-in-chief, his brother Lucius Scipio, whose intellect was insignificant, and who had no military capacity.

The reserve hitherto stationed in Lower Italy was destined for Greece, the army of Glabrio for Asia: when it became known who was to command it, 5000 veterans from the Hannibalic war voluntarily enrolled, to fight once more under their beloved leader.

In the Roman July, but according to the true time in March, the Scipios arrived at the army to commence the Asiatic campaign; but they were disagreeably surprised to find themselves instead involved, in the first instance, in an endless struggle with the desperate Aetolians.