Those dwelling immediately to the north of the Arno were extirpated.

This fate befell chiefly the Apuani, who dwelt on the Apennines between the Arno and the Magra, and incessantly plundered on the one side the territory of Pisae, on the other that of Bononia and Mutina.

Those who did not fall victims in that quarter to the sword of the Romans were transported into Lower Italy to the region of Beneventum (574); and by energetic measures the Ligurian nation, from which the Romans were obliged in 578 to recover the colony of Mutina which it had conquered, was completely crushed in the mountains which separate the valley of the Po from that of the Arno.

The fortress of Luna (not far from Spezzia), established in 577 in the former territory of the Apuani, protected the frontier against the Ligurians just as Aquileia did against the Transalpines, and gave the Romans at the same time an excellent port which henceforth became the usual station for the passage to Massilia and to Spain.

The construction of the coast or Aurelian road from Rome to Luna, and of the cross road carried from Luca by way of Florence to Arretium between the Aurelian and Cassian ways, probably belongs to the same period.
With the more western Ligurian tribes, who held the Genoese Apennines and the Maritime Alps, there were incessant conflicts.