From Drury-lane it spread along Holborn, eastward as far as Great Turnstile, and westward to Saint Giles's Pound, and so along the Tyburn-road.

Saint Andrew's, Holborn, was next infected; and as this was a much more populous parish than the former, the deaths were more numerous within it.

For a while, the disease was checked by Fleet Ditch; it then leaped this narrow boundary, and ascending the opposite hill, carried fearful devastation into Saint James's, Clerkenwell.

At the same time, it attacked Saint Bride's; thinned the ranks of the thievish horde haunting Whitefriars, and proceeding in a westerly course, decimated Saint Clement Danes.
Hitherto, the city had escaped.

The destroyer had not passed Ludgate or Newgate, but environed the walls like a besieging enemy.