Peeples cites an instance in Texas in an infant at the age of five days, which was associated with a remarkable development of the genital organs and breasts.

Van Swieten offers an example at the first month; the British Medical Journal at the second month; Conarmond at the third month.
Ysabel, a young slave girl belonging to Don Carlos Pedro of Havana, began to menstruate soon after birth, and at the first year was regular in this function.

At birth her mamma were well developed and her axillae were slightly covered with hair.

At the age of thirty-two months she was three feet ten inches tall, and her genitals and mammae resembled those of a girl of thirteen.

Her voice was grave and sonorous; her moral inclinations were not known.