There were 25 patients in all; in 22 the effect was entirely satisfactory, the loss of weight amounting to as much as 9.5 kilos (21 pounds).

Of the three cases in which the result was not satisfactory, one had nephritis with severe Graves' disease, and the third psoriasis.

Charrin has used the injections of thyroid extract with decided benefit.

So soon as the administration of the remedy was stopped the loss of weight ceased, but with the renewal of the remedy the loss of weight again ensued to a certain point, beyond which the extract seemed powerless to act.

Ewald also reports good results from this treatment of obesity.
Remarkable Instances of Obesity .-- From time immemorial fat men and women have been the object of curiosity and the number who have exhibited themselves is incalculable.