One of them killed an Indian with a knife thrust; Lewis himself shot another Indian, and the remaining six fled, carrying with them one of Lewis' horses, but losing four of their own, which the whites captured.

This was the beginning of the long series of bloody skirmishes between the Blackfeet and the Rocky Mountain explorers and trappers.

Clark, at about the same time, suffered at the hands of the Crows, who stole a number of his horses.
He is Shot by one of his Own Party.
None of the party were hurt by the Indians, but some time after the skirmish with the Blackfeet Lewis was accidentally shot by one of the Frenchmen of the party and suffered much from the wound.

Near the mouth of the Yellowstone Clark joined him, and the reunited company floated down the Missouri.

Before they reached the Mandan villages they encountered two white men, the first strangers of their own color the party had seen for a year and a half.