Marcus Aurelius was, without any doubt, a virtuous ruler, and one who had it in his heart to be just and humane; but he was an absolute ruler, that is to say, one fed entirely on his owns ideas, very ill-informed about the facts on which he had to decide, and without a free public to warn him of the errors of his ideas or the practical results of his decrees.

He ordered the persecution of the Christians without knowing what the Christians were, or what the persecution would be, and this conscientious philosopher let loose at Lyons, against the most conscientious of subjects, the zealous servility of his agents, and the atrocious passions of the mob.
The persecution of the Christians did not stop at Lyons, or with Marcus Aurelius; it became, during the third century, the common practice of the emperors in all parts of the Empire: from A.D.202 to 312, under the reigns of Septimius Severus, Maximinus the First, Decius, Valerian, Aurelian, Diocletian, Maximian, and Galerius, there are reckoned six great general persecutions, without counting others more circumscribed or less severe.

The Emperors Alexander Severns, Philip the Arabian, and Constantius Chlorus were almost the only exceptions to this cruel system; and nearly always, wherever it was in force, the Pagan mob, in its brutality or fanatical superstition, added to imperial rigor its own atrocious and cynical excesses.
But Christian zeal was superior in perseverance and efficacy to Pagan persecution.

St.Pothinus the Martyr was succeeded as bishop at Lyons by St.Irenaeus, the most learned, most judicious, and most illustrious of the early heads of the Church in Gaul.

Originally from Asia Minor, probably from Smyrna, he had migrated to Gaul, at what particular date is not known, and had settled as a simple priest in the diocese of Lyons, where it was not long before he exercised vast influence, as well on the spot as also during certain missions intrusted to him, and amongst them one, they say, to the Pope St.Eleutherius at Rome.