143.
[33] Strabo, 646.
[34] Vitruvius, i.

6.
In other cases the same planning was probably adopted, although the evidence as yet known shows only a rectangular plan of main streets, such as we have met in Pre-Macedonian Greece.

In Macedonia itself, Thessalonika, laid out perhaps about 315 B.C., had at least one main street running southwards to the sea and two more running east and west at right angles to that.[35] In Asia two Syrian towns, which occupy sites closed to Hellenic culture before Alexander, may serve as examples.

Apamea on the Orontes was built by the Macedonians, rose forthwith to importance, and retained its vigorous prosperity through the Roman Empire; in A.D.6 it was 'numbered' by Sulpicius Quirinius, then the governor of Syria, and the census showed as many as 117,000 citizens settled in the city and its adjacent 'territory'.

Its ruins seem to be mainly earlier than the Romans, and its streets may well date from its Macedonian founders.