He was sure that he was divinely sent, and that his mission was to open the way to the Indies, for the religious advancement of mankind.

If Vasco de Gama had discovered a shorter way than men knew before, Christopher Columbus should discover one shorter still, and this discovery should tend to the glory of God.

It seemed to him that the simplest way in which he could make men understand this, was to show that the Holy Sepulchre might, now and thus, be recovered from the infidel.
Far from urging geographical curiosity as an object, he proposed rather the recovery of the Holy Sepulchre.

That is, there was to be a new and last crusade, and the money for this enterprise was to be furnished from the gold of the farthest East.

He was close at the door of this farthest East; and as has been said, he believed that Cuba was the Ophir of Solomon, and he supposed, that a very little farther voyaging would open all the treasures which Marco Polo had described, and would bring the territory, which had made the Great Khan so rich, into the possession of the king of Spain.
He showed to Ferdinand and Isabella that, if they would once more let him go forward, on the adventure which had been checked untimely by the cruelty of Bobadilla, this time they would have wealth which would place them at the head of the Christian sovereigns of the world.
While he was inactive at Seville, and the great squadron was being prepared which Ovando was to command, he wrote what is known as the "Book of Prophecies," in which he attempted to convince the Catholic kings of the necessity of carrying forward the enterprise which he proposed.