He saw at once that her trouble was mental and, like a wise physician, engaged her in general conversation.
Quite possibly he knew her story, for the name of a certain actor, Pylades, was mentioned, and he noticed that her pulse at once increased in rapidity and became irregular.

On the next day he arranged that the name of another actor, Morphus, should be mentioned, and on the third day the experiment was repeated but without effect.

Then on the fourth evening it was again mentioned that Pylades was dancing, and the pulse quickened and became irregular, so he concluded that she was in love with Pylades.

He tells how he was first called to treat the Emperor Marcus Aurelius, who had a stomach-ache after eating too much cheese.

He treated the case so successfully that the Emperor remarked, "I have but one physician, and he is a gentleman." He seems to have had good fees, as he received 400 aurei (about 2000) for a fortnight's attendance upon the wife of Boethus.
He left Rome for a time in 168 A.D.and returned to Pergamon, but was recalled to Rome by the Emperor, whom he accompanied on an expedition to Germany.