Here he very greatly distinguished himself, and in numberless engagements was always successful, so that he became known as Zeno the Unconquered.
When Pisani was appointed captain general, in April, 1378, he was appointed governor of Negropont, and soon afterwards received a separate naval command.

He had been lost sight of for many months, prior to his appearance so opportunely before Brondolo, and he now confirmed to the doge the news that had been received shortly before.
He had captured nearly seventy Genoese vessels, of various sizes, had cruised for some time in sight of Genoa, struck a heavy blow at her commerce, and prevented the despatch of the reinforcements promised to Doria.

Among the vessels taken was one which was carrying three hundred thousand ducats from Genoa.
He reported himself ready with his men to take up the brunt of the siege forthwith, and selecting Brondolo as the most dangerous position, at once landed his crews.

The stores on board ship were also brought ashore, and proved ample for the present necessities of the army.
In a few days, he sailed with his galleys and recaptured Loredo, driving out the Paduan garrison there.

This conquest was all important to Venice, for it opened their communication with Ferrara, and vast stores of provisions were at once sent by their ally to Venice, and the pressure of starvation immediately ceased.
The siege of Brondolo was now pushed on, and on the 22nd of January the great bombard, the Victory, so battered the wall opposite to it that it fell suddenly, crushing beneath its ruins the Genoese commander, Doria.
The change which three weeks had made in the appearance of the Venetian forces was marvellous.