It extended to many places; but most of all it afflicted Milan.
It is probable that these disasters were among the causes of Petrarch's leaving Milan.

He settled at Padua, when the plague had not reached it.
At this time, Petrarch lost his son John.

Whether he died at Milan or at Padua is not certain, but, wherever he died, it was most probably of the plague.

John had not quite attained his twenty-fourth year.
In the same year, 1361, he married his daughter Francesca, now near the age of twenty, to Francesco di Brossano, a gentleman of Milan.

Petrarch speaks highly of his son-in-law's talents, and of the mildness of his character.