The whole being of substance is as a substratum for attributes.

Thus time and space should be attributes of the substance.

This they palpably are not, if the matter be the substance of nature, since it is impossible to express spatio-temporal truths without having recourse to relations involving relata other than bits of matter.
I waive this point however, and come to another.

It is not the substance which is in space, but the attributes.

What we find in space are the red of the rose and the smell of the jasmine and the noise of cannon.