The whole which is present for discrimination is posited in sense-awareness as necessary for the discriminated parts.

An isolated event is not an event, because every event is a factor in a larger whole and is significant of that whole.
There can be no time apart from space; and no space apart from time; and no space and no time apart from the passage of the events of nature.

The isolation of an entity in thought, when we think of it as a bare 'it,' has no counterpart in any corresponding isolation in nature.

Such isolation is merely part of the procedure of intellectual knowledge.
The laws of nature are the outcome of the characters of the entities which we find in nature.

The entities being what they are, the laws must be what they are; and conversely the entities follow from the laws.