The disease early manifests itself, and I have often seen well-marked enlargement in children as young as eight.

Turn any street corner in any town of importance in Western Yunnan and you will meet half a dozen cases; there must be few families in the western portion of the province free from the taint.
On a day, for example, like this (May 5th), when the road was more than usually mountainous, though that may have been an accident, my chairen was a "thickneck" and my two soldiers were "thicknecks." At the village of Huanglien-pu, where I had lunch, the landlady of the inn had a goitrous neck that was swelled out half-way to the shoulder, and her son was a slobbering-mouthed cretin with the intelligence of an animal.

And among the people who gathered round me in a dull, apathetic way every other one was more or less marked with the disease and its attendant mental phenomena.

Again, at the inn in a little mountain village, where we stopped for the night, mother, father, and every person in the house, to the number of nine, above the age of childhood was either goitrous or cretinous, dull of intelligence, mentally verging upon dementia in three cases, in two of which physical growth had been arrested at childhood.
Rarely during my journey to Burma was I offended by hearing myself called "_Yang kweitze_" (foreign devil), although this is the universal appellation of the foreigner wherever Mandarin is spoken in China.
To-day, however, (May 6th), I was seated at the inn in the town of Chutung when I heard the offensive term.

I was seated at a table in the midst of the accustomed crowd of Chinese.