It became a vital center to the Baptist denomination.

From it, at its second meeting, proceeded effective measures for the promotion of education in the ministry, and, under the conviction that "western as well as eastern regions are given to the Son of God as an inheritance," large plans for home missions at the West.
Thus the great debt which the English Congregationalists had owed to the Baptists for heroic leadership in the work of foreign missions was repaid with generous usury by the Congregationalists to the Baptists of America.

From this time forward the American Baptists came more and more to be felt as a salutary force in the religious life of the nation and the world.

But against what bitter and furious opposition on the part of the ancient ignorance the new light had to struggle cannot easily be conceived by those who have only heard of the "Hard-Shell Baptist" as a curious fossil of a prehistoric period.[255:1] The American Board of Commissioners for Foreign Missions continued for twenty-seven years to be the common organ of foreign missionary operations for the Congregationalists, the Presbyterians, and the Dutch and German Reformed churches.

In the year 1837 an official Presbyterian Board of Missions was erected by the Old-School fragment of the disrupted Presbyterian Church; and to this, when the two fragments were reunited, in 1869, the contributions of the New-School side began to be transferred.